• Joint effect of myocardial infarction and obesity on the risk of venous thromboembolism: The Tromsø Study 

      Sejrup, Joakim Knutsen; Tøndel, Birgitte Gladsø; Morelli, Vania Maris; Løchen, Maja-Lisa; Njølstad, Inger; Mathiesen, Ellisiv B.; Wilsgaard, Tom; Hansen, John Bjarne; Brækkan, Sigrid Kufaas (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-19)
      Background: Myocardial infarction (MI) is associated with an increased risk of venous thromboembolism (VTE). Obesity is a recognized risk factor for both MI and VTE. Whether obesity further increases the risk of VTE in MI patients is scarcely investigated.<p> <p>Aim: To study the joint effect of MI and obesity on the risk of VTE. <p>Methods: Study participants (n = 29 410) were recruited from ...
    • Myocardial infarction as a transient risk factor for incident venous thromboembolism: Results from a population-based case-crossover study 

      Sejrup, Joakim Knutsen; Børvik, Trond; Grimnes, Gro; Isaksen, Trond; Hindberg, Kristian; Hansen, John-Bjarne; Morelli, Vania Maris; Brækkan, Sigrid Kufaas (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-16)
      Patients with myocardial infarction (MI) are at increased short-term risk of venous thromboembolism (VTE). The mechanisms behind this association are unclear. We aimed to investigate the impact of acute MI as a transient risk factor for incident VTE while taking other concomitant VTE risk factors into account. We conducted a case–crossover study of VTE patients (<i>n</i> = 707) recruited from the ...
    • Myocardial infarction, prothrombotic genotypes, and venous thrombosis risk: The Tromsø Study 

      Sejrup, Joakim Knutsen; Morelli, Vania Maris; Løchen, Maja-Lisa; Njølstad, Inger; Mathiesen, Ellisiv B.; Wilsgaard, Tom; Hansen, John-Bjarne; Brækkan, Sigrid Kufaas (Journal article; Tidsskriftartikkel; Peer reviewed; Master thesis; Mastergradsoppgave, 2020-01-27)
      <p><i>Background - </i>The risk of venous thromboembolism (VTE) is increased after a myocardial infarction (MI). Some prothrombotic genotypes associated with VTE have also been associated with risk of MI. Whether prothrombotic single‐nucleotide polymorphisms (SNPs) further increase the risk of VTE in MI patients is scarcely investigated. <p><i>Aim - </i>To study the combined effect of MI and ...
    • Prothrombotic Single Nucleotide Polymorphisms and Risk of Myocardial Infarction: A Narrative Review of the Literature 

      Sejrup, Joakim Knutsen (Master thesis; Mastergradsoppgave, 2020-08-24)
      Background: Environmental risk factors for myocardial infarction (MI) have been extensively investigated. In addition, family history of MI is an important risk factor for the disease. Several prothrombotic genotypes are well-established risk factors for venous thrombosis. However, the role of prothrombotic genotypes as risk factors for arterial thrombosis is less emphasized. Aim: To create a ...
    • Risk Factors and Triggers of Venous Thromboembolism in Patients with Myocardial Infarction 

      Sejrup, Joakim Knutsen (Doctoral thesis; Doktorgradsavhandling, 2022-06-17)
      <p>During the past decades, extensive data from the general population have revealed that patients with acute myocardial infarction (MI) are at increased risk of venous thromboembolism (VTE, i.e., deep vein thrombosis [DVT] and pulmonary embolism [PE]). The risk is highest in the initial 0-6 months following an acute MI, and declines rapidly thereafter. The explanation for the observed association ...
    • The Role of Stroke as a Trigger for Incident Venous Thromboembolism: Results from a Population-based Case-Crossover Study 

      Morelli, Vania Maris; Sejrup, Joakim Knutsen; Småbrekke, Birgit; Rinde, Ludvig B; Grimnes, Gro; Isaksen, Trond; Hansen, John-Bjarne; Hindberg, Kristian; Brækkan, Sigrid Kufaas (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-22)
      Stroke is associated with a short-term increased risk of subsequent venous thromboembolism (VTE). It is unclear to what extent this association is mediated by strokerelated complications that are potential triggers for VTE, such as immobilization and infection. We aimed to investigate the role of acute stroke as a trigger for incident VTE while taking other concomitant VTE triggers into account. ...